Loretta Y Y Chan Selected Research

polymeric IgA

10/2008	BMP-7 protects mesangial cells from injury by polymeric IgA.
1/2003	Polymeric IgA increases the synthesis of macrophage migration inhibitory factor by human mesangial cells in IgA nephropathy.

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Loretta Y Y Chan Research Topics

Disease

21	IGA Glomerulonephritis (IGA Nephropathy) 01/2021 - 09/2002
18	Inflammation (Inflammations) 04/2024 - 12/2004
11	Fibrosis (Cirrhosis) 01/2023 - 12/2003
10	Diabetic Nephropathies (Diabetic Nephropathy) 01/2018 - 06/2006
6	Albuminuria 01/2019 - 01/2010
4	Chronic Renal Insufficiency 01/2023 - 02/2015
4	Proteinuria 01/2018 - 08/2005
3	Ischemia 04/2024 - 06/2012
3	Acute Kidney Injury (Acute Renal Failure) 04/2024 - 06/2012
3	Necrosis 01/2009 - 01/2003
3	Glomerulonephritis 01/2005 - 08/2004
2	Hypoxia (Hypoxemia) 01/2023 - 11/2020
2	Vascular System Injuries 01/2023 - 12/2021
2	Ureteral Obstruction 12/2021 - 11/2020
2	Insulin Resistance 01/2020 - 01/2010
2	Hypertrophy 05/2013 - 09/2011
2	Hematuria 02/2011 - 01/2005
2	Type 2 Diabetes Mellitus (MODY) 12/2010 - 01/2010
2	Chronic Kidney Failure (Chronic Renal Failure) 02/2009 - 12/2003
1	Sepsis (Septicemia) 04/2024
1	Microvascular Rarefaction 01/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 12/2022
1	Neoplasms (Cancer) 12/2021
1	Reperfusion Injury 11/2020
1	Chronic Disease (Chronic Diseases) 01/2020
1	Obesity 01/2019
1	Kidney Diseases (Kidney Disease) 11/2017
1	Wounds and Injuries (Trauma) 05/2013

Drug/Important Bio-Agent (IBA)

14	Immunoglobulin A (IgA)IBA 01/2021 - 09/2002
6	Transforming Growth Factor beta (TGF-beta)IBA 01/2009 - 12/2003
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2009 - 01/2003
5	CollagenIBA 11/2020 - 05/2013
4	Interleukin-6 (Interleukin 6)IBA 04/2024 - 01/2008
4	Proteins (Proteins, Gene)FDA Link 12/2021 - 01/2003
4	CreatinineIBA 02/2016 - 01/2009
4	Angiotensin IIIBA 10/2011 - 12/2004
3	CateninsIBA 12/2022 - 01/2018
3	AlbuminsIBA 10/2014 - 05/2011
3	Glucose (Dextrose)FDA LinkGeneric 10/2014 - 01/2010
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 09/2011 - 02/2011
3	CytokinesIBA 05/2011 - 12/2004
3	PPAR-gamma AgonistsIBA 08/2009 - 06/2006
3	PPAR gammaIBA 08/2009 - 10/2008
2	salicylhydroxamic acid (SHAM)IBA 04/2024 - 06/2012
2	InflammasomesIBA 04/2024 - 01/2018
2	Thrombin FDA Link 01/2023 - 11/2020
2	vorapaxarIBA 01/2023 - 11/2020
2	kallistatinIBA 12/2021 - 02/2016
2	Conditioned Culture MediaIBA 01/2021 - 08/2005
2	Fibronectins (Fibronectin)IBA 11/2020 - 10/2008
2	Toll-Like Receptor 4IBA 01/2020 - 01/2012
2	Urea (Carbamide)FDA LinkGeneric 01/2018 - 05/2013
2	NitrogenIBA 01/2018 - 05/2013
2	Bone Morphogenetic Protein 7IBA 02/2015 - 10/2008
2	LigandsIBA 05/2013 - 01/2012
2	Toll-Like Receptors (Toll-Like Receptor)IBA 05/2013 - 01/2012
2	nephrinIBA 01/2010 - 01/2009
2	polymeric IgAIBA 10/2008 - 01/2003
2	Macrophage Migration-Inhibitory FactorsIBA 08/2004 - 01/2003
1	Long Noncoding RNAIBA 04/2024
1	Peptide Hydrolases (Proteases)FDA Link 01/2023
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2023
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023
1	LipopolysaccharidesIBA 12/2022
1	Biomarkers (Surrogate Marker)IBA 12/2021
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 12/2021
1	Syk KinaseIBA 01/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Nonesterified Fatty Acids (NEFA)IBA 01/2020
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2019
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2019
1	Biotin (Vitamin H)FDA Link 01/2019
1	LipidsIBA 01/2018
1	EndotoxinsIBA 01/2018
1	Bovine Serum AlbuminIBA 01/2018
1	Tamoxifen FDA LinkGeneric 01/2018
1	Complement C5a (Complement 5a)IBA 01/2018
1	NOX-D21IBA 01/2018
1	Tissue Kallikreins (Tissue Kallikrein)IBA 02/2016
1	Plasminogen Activator Inhibitor 1IBA 02/2016
1	advanced glycation end products-bovine serum albuminIBA 10/2014
1	Human Serum Albumin FDA LinkGeneric 10/2014
1	Blood Glucose (Blood Sugar)IBA 05/2013
1	CC ChemokinesIBA 05/2013
1	OsteopontinIBA 05/2013
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 05/2013
1	CRX-526IBA 05/2013
1	LeptinIBA 08/2012
1	Streptozocin (Streptozotocin)FDA Link 01/2012
1	AldosteroneIBA 10/2011
1	InterleukinsIBA 05/2011
1	Advanced Glycation End ProductsIBA 05/2011
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 02/2011

Therapy/Procedure

2	Therapeutics 11/2017 - 01/2005
2	Peritoneal Dialysis 08/2012 - 10/2007
2	Continuous Ambulatory Peritoneal Dialysis (CAPD) 05/2009 - 02/2009
1	Ligation 04/2024
1	Punctures 04/2024
1	Intraperitoneal Injections 01/2018
1	Injections 11/2017